About

I am Choonzo Nachoobe Chiyumba MRSC, a chemist and Cambridge Trust Scholar. I have successfully passed my PhD viva at the University of Cambridge and am awaiting graduation. I am actively seeking roles in synthetic chemistry, medicinal chemistry, chemical biology, biocatalysis and drug discovery.

My scientific journey

My scientific training began with a BSc in Chemical Biology at the University of Zambia and continued through first-class postgraduate training in chemistry at Rhodes University. During my MSc, I designed and synthesised more than 15 π-extended BODIPY dyes and cationic porphyrins for photodynamic anticancer and antimicrobial research. By connecting molecular structure with biological performance, I developed an early interest in how deliberate chemical design can solve problems in human health and contributed to three peer-reviewed publications.

At Cambridge, my research developed along two independent lines. As a synthetic organic chemist, I built a 25+ compound substrate library spanning exocyclic-methylene and diazirine scaffolds, developed multi-step coumarin and carbene-precursor routes, and completed purification and structure confirmation by NMR and HRMS. This work strengthened my capabilities in route design, scaffold diversification, reaction optimisation and small-molecule characterisation.

In parallel, my doctoral research explores synthetic porphyrin–protein conjugates as artificial metalloenzymes. I designed and synthesised Ir(III) and Zn(II) metalloporphyrin cofactors, engineered cytochrome b562 protein variants, and developed quantitative workflows to understand protein–cofactor assembly. Together, these two pillars give me depth in synthetic chemistry and the ability to apply molecules within complex biological systems. They also support a wider scientific goal: developing chemical transformations that combine molecular precision with greater selectivity, milder conditions and a more sustainable approach to chemical production.

Science with purpose

I am motivated by chemistry that can move from molecular insight towards meaningful health impact. My long-term ambition is to apply my experience in molecular design, catalysis and chemical biology to medicinal chemistry and drug discovery—particularly for malaria and other diseases that disproportionately affect communities across Africa.

This ambition is personal as well as scientific. It is why I am building the range to work across conventional synthetic chemistry and engineered biological systems: I want to help create new therapeutic possibilities, not simply study molecules in isolation.

In October 2025, I was an invited delegate at Medicines for Malaria Venture’s Science of Malaria Medicine Symposium in Geneva. Engaging with contemporary challenges in malaria and anti-infective drug discovery reinforced the direction in which I want to take my chemistry: towards therapeutics with meaningful global-health impact.

What I bring

Synthetic breadthMulti-step route design, analogue libraries, reaction optimisation, purification and structure confirmation across 40+ compounds.
Artificial metalloenzyme systemsMetalloporphyrin synthesis, protein engineering, cofactor assembly, quantitative binding and preliminary catalysis.
Evidence-led discoveryI combine NMR, HRMS, HPLC and spectroscopy with quantitative binding and structure–activity analysis.
Leadership with resultsI have won competitive RSC funding, supported research-funding decisions and delivered a £40,000 partnership campaign—150% of target.

Beyond the laboratory

At the University of Cambridge, I have trained and supported more than 20 undergraduate students in laboratory technique, risk assessment, data interpretation and scientific problem-solving. Teaching has strengthened my ability to explain complex science clearly, adapt to different levels of experience and create an environment in which others can develop confidence.

My contribution also extends into scientific leadership, innovation and community building. Through EnterpriseTECH at the Cambridge Judge Entrepreneurship Centre, I evaluated innovative technologies, translated technical ideas into persuasive funding pitches and produced market-facing video content. The experience strengthened my ability to connect scientific evidence with commercial opportunity and communicate value beyond the laboratory.

As a non-executive board member supporting the Cambridge-Africa ALBORADA Research Fund, I review research proposals and contribute to funding decisions. I have secured £2,500 in competitive Royal Society of Chemistry funding for scientific engagement and international presentation, and while leading corporate relations for the African Society of Cambridge University, I helped raise £40,000 through a revised partnership strategy.

Across research, teaching and leadership, the common thread is clear: I turn ambitious ideas into structured work, measurable evidence and outcomes that create opportunities for others.