About

I am Choonzo Chiyumba MRSC, a Zambian synthetic chemist and chemical biologist based in Cambridge. I work at the interface of molecular synthesis, protein engineering and analytical science.

My scientific journey

My training began in chemical biology at the University of Zambia and developed through first-class postgraduate degrees at Rhodes University. During my MSc, I designed and synthesised photoactive porphyrin and BODIPY compounds, established structure–activity relationships through biological evaluation, and contributed to three peer-reviewed publications.

At the University of Cambridge, my doctoral research moved from small molecules into engineered biological systems. I synthesised synthetic metalloporphyrin cofactors, engineered cytochrome b₅₆₂ protein variants and created analytical pipelines to study protein–cofactor assembly. This combination of chemistry and protein science has shaped how I approach research: design carefully, measure rigorously and keep the intended function in view.

Science with purpose

Malaria remains an urgent scientific and public-health challenge. I am motivated to move towards medicinal chemistry and drug discovery, applying molecular design to treatments for malaria and other diseases that disproportionately affect communities across Africa.

My interests also extend to sustainable development. Systems thinking and prior experience in infrastructure delivery have taught me to consider not only whether an innovation works, but also the institutions, people and practical conditions required for it to create value.

How I work

CuriousI enjoy questions that require learning across disciplinary boundaries.

RigorousI build conclusions from reproducible experiments and careful analysis.

Purpose-ledI am drawn to research with a credible path to improving lives.

CollaborativeI value generous teamwork, mentorship and clear communication.

Beyond research

I am a University of Cambridge demonstrator and supervisor, supporting students in laboratory technique, risk assessment and scientific problem-solving. As a non-executive board member of the Cambridge-Africa ALBORADA Research Fund, I review research proposals and contribute to funding decisions. I have also led corporate relations for the African Society of Cambridge University, raising £40,000—150% of target—through a revised fundraising strategy.